Jose Antonio Esquivel Gaytan

Professional Profile

A dedicated PhD candidate in Experimental Cardiology at UMCG, I integrate clinical insights with cutting-edge research. I specialize in high-throughput screening, cardiovascular biomarker analysis, and nanoparticle-based drug delivery.

Expert in bridging clinical practice and molecular research.
Proficient in AI-driven data analysis and innovative experimental design.
Committed to advancing translational medicine and improving patient outcomes.

Relevant Experience

Nov 2018 – Present

Doctoral Researcher

University Medical Center Groningen, Netherlands

Project Leadership: Coordinated multi-disciplinary projects and optimized 5-oxoprolinase (OPLAH) activity to mitigate oxidative stress in heart failure.
Innovative Screening: Developed a high-throughput platform integrating proteomics and nanoparticle-based delivery.
Data & Biomarkers: Designed workflows for cardiovascular biomarker analysis with AI-driven visualization.
Team Collaboration: Supervised students and led meetings to integrate clinical insights into experimental design.

Mar 2018 – Oct 2018

Clinical Supervisor and Lecturer

Universidad del Valle de México, Mexico

Guided medical students during clinical rotations while delivering comprehensive educational programs.
Ensured adherence to high training standards in both academic and clinical settings.

Nov 2017 – May 2018

Medical Researcher

Science iN, Mexico City Area, Mexico

Maintained data integrity and standardized documentation protocols across trial sites.
Authored technical and regulatory reports in close collaboration with clinical teams.

Jan 2015 – Dec 2015

Community General Practitioner (Clinical Research Intern)

IMEMIC, Mexico City, Mexico

Clinical Trials Support: Managed trial operations and maintained high documentation standards.
Process Optimization: Streamlined laboratory procedures and implemented sample tracking systems.
Patient Care: Delivered primary consultations and organized educational initiatives.

Jan 2014 – Dec 2014

Clinical Intern (Chief)

ISSSTE MX, Querétaro, Mexico

Comprehensive Rotations: Completed rotations in Family Medicine, Pediatrics, and Surgery.
Leadership: Mentored interns and optimized clinical workflows.

Skills

Project Management & Communication

Project Management

Team Leadership

Cross-functional Collaboration

Scientific Writing

Protocol Development

Regulatory Compliance

Translational & Clinical

Translational Medicine

Clinical Research

Systematic Reviews

Wet Lab & Molecular

Molecular Biology

Protein Purification

Cell Culture

Western Blot

qRT-PCR

LC-MS

AI & Data

Data Analysis

AI-driven Analytics

Machine Learning

Programming & Tools

Python

R

HTML

Visual Studio

Statistical Analysis

Education

PhD in Biomedical Sciences

University of Groningen

Nov 2018 – Feb 2025

MSc in Nanotechnology and Regenerative Medicine

UCL

Sep 2016 – Nov 2017

Honors: Awarded with distinction
Project: Photochemical Internalisation for Pancreatic Cancer Treatment
Key Modules: Translational Medicine, Nanotechnology, Biomaterials, Tissue Engineering

MBBS (Bachelor of Medicine, Bachelor of Surgery)

Universidad Nacional Autónoma de México

Aug 2009 – Nov 2016

Graduated with outstanding performance

Publications

Esquivel-Gaytan, A., et al. (2024). "404-error 'Disease not found': Unleashing the translational potential of -omics approaches beyond traditional disease classification in heart failure research." European Journal of Heart Failure. DOI: 10.1002/ejhf.3268
This study integrates omics technologies to challenge traditional heart failure classifications and reveal novel disease mechanisms.
Esquivel-Gaytan, A., et al. (2023). "A high-throughput screening strategy identifies adenosine 5'-monophosphate as a novel enhancer of the cardio-protective enzyme 5-oxoprolinase (OPLAH)." European Heart Journal, 44(Supplement_2), ehad655.3130. DOI: 10.1093/eurheartj/ehad655.3130
Describes a screening platform that discovered AMP as a modulator of OPLAH, potentially enhancing cardiac protection.
Vermeer, M.C.S.C., et al. (2022). "A translation re-initiation variant in KLHL24 causes epidermolysis bullosa simplex and dilated cardiomyopathy via intermediate filament degradation." The British Journal of Dermatology, 187(6), 1045-1048. DOI: 10.1111/bjd.21832
Explores the molecular pathways linking a KLHL24 variant to both skin and cardiac conditions.

Languages

Spanish: Native
English: C1
Dutch: B1/B2
French: A2

Certifications

Good Clinical Practice – NDAT CTN 2025
Article 9 – Experiments on Animals Act License
ML-1 Laboratory Certificate
Driving License AM-B

Interests

CrossFit Athlete

Artificial Intelligence

Traveling

Animal Welfare

Contact

Location: Groningen, Netherlands

Email: j.esquivel.gaytan@gmail.com

LinkedIn: linkedin.com/in/joseantonio-esquivel-gaytan89

ResearchGate: Antonio-Gaytan-2

ORCID: 0000-0001-6974-1825

Website: drjaeg.com

Get in Touch