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Physician-Scientist (MD, MSc, PhDc)

Auditable AI with Clinical Precision.

Bridging the gap between Experimental Cardiology and Generative AI. Building systems where the expert remains the architect.

Antonio Esquivel Gaytan
Core Engine
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Core Expertise

Validation-first GenAI

Moving beyond chatbots. I design systems with strict schema constraints, source-grounding, and human-in-the-loop e-signatures to eliminate hallucinations in clinical reports.

Build Fast, Ship Clean

From local LLMs (Ollama) to secure Cloud (Bedrock). I build reproducible MVPs using FastAPI and Docker that respect patient data privacy boundaries.

Translational Cardiology

PhD research in Heart Failure and oxidative stress. I bring wet-lab methodology (Z', S/B robustness) to AI validation.

Clinical Ops & GCP

Translating protocols into structured visit schedules. LLM-assisted tools that reduce manual workload while maintaining full audit readiness.

Education

  • PhD Exp. Cardiology, UMCG (2018-Present)
  • MSc Nanotech & RegMed, UCL (2016-2017)
  • MD Physician, UNAM Mexico (2009-2016)

Compliance & Certs

ICH-GCP E6(R3) Animal Exp. (Art. 9) MDR Awareness AI Ethics (Helsinki) Hugging Face LLM

Technical Stack

Amazon Bedrock Ollama FastAPI Docker Python Claude/Gemini

Concepts & Prototypes

Privacy-First

Offline RAG for HF Guidelines

Local assistant (Ollama) providing citation-based answers from guidelines without PHI exposure.

Concept

Lab SOP Assistant

On-device voice assistant for stepwise execution of laboratory protocols with audit logging.

MVP

Medication Adherence

Privacy-focused tool for medication follow-up (PrEP) with clear clinical responsibility boundaries.

"The question isn't whether AI will be adopted, but by whom it will be constrained. I ensure we don't outsource clinical judgment."

Selected Work

Jun — Sep 2025

Clinical Research & AI Lead

Pangaea Oncology, Barcelona

Orchestrated LLM workflows (Bedrock/Claude) for clinical reporting. Achieved ~80% reduction in hallucinations via prompt engineering.

2024 — 2025

Co-founder & Tech Lead

QGuard-Med, Groningen

Developed a FastAPI/Docker MVP for cardiovascular patient prioritization. Finalist at "Break The Gap 2025".

2018 — Present

PhD Researcher

UMCG, Netherlands

Experimental Cardiology. Investigating 5-oxoproline/OPLAH and oxidative stress. High-throughput assays and data analysis.

Publications

View ORCID
Eur J Heart Fail (2024)

404-error "Disease not found": Unleashing the potential of omics.

ESC Heart Fail (2025)

Glutathione deficiency and heart failure: a systematic review.

Redox Biology (Review)

Elevated 5-Oxoproline Levels Associate with Adverse Outcomes.

Under Review
Br J Dermatol (2022)

A translation re-initiation variant in KLHL24 and cardiomyopathy.

Eur Heart J (2023)

High-throughput screening strategy identifies AMP as a novel OPLAH enhancer.