Physician-Scientist

Auditable AI for clinical workflows.

Physician-Scientist (MD, MSc, PhDc) bridging Experimental Cardiology & Applied AI. I build systems that are safe, regulation-aware, and keep clinicians firmly in control.

"The challenge isn't just adopting AI—it's ensuring we don't outsource clinical judgment to tools we don't fully understand. I build workflows where AI suggests, but the expert decides."
Antonio Esquivel Gaytan

Core Expertise

Where clinical rigour meets software engineering.

Validation-first GenAI

Moving beyond "chatbots" to auditable workflows. I design systems with strict schema constraints, source-grounding, and mandatory human-in-the-loop (HITL) e-signatures.

Clinical Ops & GCP

Translating protocols into structured visit schedules. My implementation of LLM-assisted inventory tools reduced manual workload by ~90% while maintaining audit readiness.

Translational Cardiology

PhD research in Heart Failure and oxidative stress. I bring the same methodological rigour from wet-lab high-throughput screening to AI validation (Z', S/B robustness).

Build fast, ship clean

From local LLMs (Ollama) to cloud deployments (Amazon Bedrock). I build reproducible MVPs using FastAPI and Docker that respect data privacy boundaries.

"The question isn't whether AI will be adopted, but by whom it will be constrained. If we fail to define that now, we risk outsourcing clinical judgement to tools we do not fully understand."

— From my ethos on Responsible AI

Experience

Recent roles and applied projects.

Jun 2025 – Sep 2025

Clinical Research & AI Lead

Pangaea Oncology (Barcelona)

Orchestrated LLM workflows (Bedrock/Claude) for clinical reporting. Achieved ~80% reduction in hallucinations via prompt engineering and mandatory expert review layers.

2024 – 2025

Co-founder (Tech Lead)

QGuard-Med (Groningen)

Developed a FastAPI/Docker MVP for cardiovascular patient prioritization. Finalist at "Break The Gap 2025" for integrating biomarkers into transparent waitlist logic.

2018 – Present

PhD Researcher

UMCG (Netherlands)

Experimental Cardiology. Investigating 5-oxoproline/OPLAH and oxidative stress. Focus on high-throughput assays, robust data analysis, and cardiorenal interactions.

Credentials

Compliance & Certifications

ICH-GCP E6(R3) Animal Experiments (Art. 9) MDR Awareness GDPR/Privacy

Technical Ecosystem

Tools I use to build auditable systems:

Amazon Bedrock Ollama (Local) Claude / Gemini FastAPI Docker Python

Selected Publications

Peer-reviewed research and high-impact abstracts.

Eur J Heart Fail

404-error "Disease not found": Unleashing the translational potential of omics

Co-authored work integrating omics approaches to challenge conventional heart failure disease classification.

Br J Dermatol

A translation re-initiation variant in KLHL24 and dilated cardiomyopathy

Investigation into intermediate filament degradation variants connecting dermatological and cardiac phenotypes.

Redox Biology

Elevated 5-Oxoproline Levels Associate with Adverse Outcomes in Heart Failure

Translational study linking 5-oxoproline accumulation to TGF-α and clinical outcomes in cardiorenal syndrome.

Eur Heart J

A high-throughput screening strategy identifies AMP as a novel OPLAH enhancer

Conference abstract detailing the screening strategy for 5-oxoprolinase (OPLAH) enhancing molecules.