Jose Antonio Esquivel Gaytan
MD, MSc, PhD Candidate
Physician-Scientist | Translational Medicine | Research Innovator
Personal Information
- Nationality: Dutch
- Current Position: PhD Candidate
- Affiliation: Experimental Cardiology, Groningen, Netherlands
- Email: j.esquivel.gaytan@gmail.com
Professional Profile
A dedicated PhD candidate in Experimental Cardiology at UMCG, I integrate clinical insights with cutting-edge research. I specialize in high-throughput screening, cardiovascular biomarker analysis, and nanoparticle-based drug delivery.
- Expert in bridging clinical practice and molecular research.
- Proficient in AI-driven data analysis and innovative experimental design.
- Committed to advancing translational medicine and improving patient outcomes.
Relevant Experience
Nov 2018 – Present
Doctoral Researcher
University Medical Center Groningen, Netherlands
- Project Leadership: Coordinated multi-disciplinary projects and optimized 5-oxoprolinase (OPLAH) activity to mitigate oxidative stress in heart failure.
- Innovative Screening: Developed a high-throughput platform integrating proteomics and nanoparticle-based delivery.
- Data & Biomarkers: Designed workflows for cardiovascular biomarker analysis with AI-driven visualization.
- Team Collaboration: Supervised students and led meetings to integrate clinical insights into experimental design.
Mar 2018 – Oct 2018
Clinical Supervisor and Lecturer
Universidad del Valle de México, Mexico
- Guided medical students during clinical rotations while delivering comprehensive educational programs.
- Ensured adherence to high training standards in both academic and clinical settings.
Nov 2017 – May 2018
Medical Researcher
Science iN, Mexico City Area, Mexico
- Maintained data integrity and standardized documentation protocols across trial sites.
- Authored technical and regulatory reports in close collaboration with clinical teams.
Jan 2015 – Dec 2015
Community General Practitioner (Clinical Research Intern)
IMEMIC, Mexico City, Mexico
- Clinical Trials Support: Managed trial operations and maintained high documentation standards.
- Process Optimization: Streamlined laboratory procedures and implemented sample tracking systems.
- Patient Care: Delivered primary consultations and organized educational initiatives.
Jan 2014 – Dec 2014
Clinical Intern (Chief)
ISSSTE MX, Querétaro, Mexico
- Comprehensive Rotations: Completed rotations in Family Medicine, Pediatrics, and Surgery.
- Leadership: Mentored interns and optimized clinical workflows.
Skills
Project Management & Communication
Translational & Clinical
Wet Lab & Molecular
AI & Data
Programming & Tools
Education
PhD in Biomedical Sciences
University of Groningen
Nov 2018 – Feb 2025
MSc in Nanotechnology and Regenerative Medicine
UCL
Sep 2016 – Nov 2017
- Honors: Awarded with distinction
- Project: Photochemical Internalisation for Pancreatic Cancer Treatment
- Key Modules: Translational Medicine, Nanotechnology, Biomaterials, Tissue Engineering
MBBS (Bachelor of Medicine, Bachelor of Surgery)
Universidad Nacional Autónoma de México
Aug 2009 – Nov 2016
- Graduated with outstanding performance
Publications
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Esquivel-Gaytan, A., et al. (2024). "404-error 'Disease not found': Unleashing the translational potential of -omics approaches beyond traditional disease classification in heart failure research."
European Journal of Heart Failure. DOI: 10.1002/ejhf.3268
This study integrates omics technologies to challenge traditional heart failure classifications and reveal novel disease mechanisms.
-
Esquivel-Gaytan, A., et al. (2023). "A high-throughput screening strategy identifies adenosine 5'-monophosphate as a novel enhancer of the cardio-protective enzyme 5-oxoprolinase (OPLAH)."
European Heart Journal, 44(Supplement_2), ehad655.3130. DOI: 10.1093/eurheartj/ehad655.3130
Describes a screening platform that discovered AMP as a modulator of OPLAH, potentially enhancing cardiac protection.
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Vermeer, M.C.S.C., et al. (2022). "A translation re-initiation variant in KLHL24 causes epidermolysis bullosa simplex and dilated cardiomyopathy via intermediate filament degradation."
The British Journal of Dermatology, 187(6), 1045-1048. DOI: 10.1111/bjd.21832
Explores the molecular pathways linking a KLHL24 variant to both skin and cardiac conditions.
Languages
- Spanish: Native
- English: C1
- Dutch: B1/B2
- French: A2
Certifications
- Good Clinical Practice – NDAT CTN 2025
- Article 9 – Experiments on Animals Act License
- ML-1 Laboratory Certificate
- Driving License AM-B
Interests
CrossFit Athlete
Artificial Intelligence
Traveling
Animal Welfare
Contact
Location: Groningen, Netherlands
Email: j.esquivel.gaytan@gmail.com
LinkedIn: linkedin.com/in/joseantonio-esquivel-gaytan89
ResearchGate: Antonio-Gaytan-2
ORCID: 0000-0001-6974-1825
Website: drjaeg.com
Get in Touch